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The association between physical activity and depressive symptoms at baseline was evaluated using multivariate linear and logistic regression models.
Physical disability at baseline was evaluated using the basic Activities of Daily Living [ 17] that investigates 6 domains providing a score ranging from 0 (total disability) to 6 (no disability).
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Throughout the study, lesions measured at baseline were evaluated using the same technique (CT or contrast-enhanced US).
Biomarker data were log2-transformed, and changes from baseline were evaluated using one-sample t tests.
Variables associated with kinesiophobia at baseline were evaluated using multivariate linear regression analyses.
Dose profiles for mean changes from baseline were evaluated using weighted MSM with a repeated measures model.
Within-group changes from open-label baseline were evaluated using paired t tests; categorical differences were assessed by Fisher exact test.
If an overall effect was identified (LPS × time interaction), the estimated individual differences from baseline were evaluated using the Tukey-Kramer adjustment for multiple comparisons.
Comparisons between the treatment groups in age, weight, height, BMI, A1C, and FPG at baseline were evaluated using a one-way ANOVA model with treatment as a factor.
Differences between subjects with low or high HFF at baseline were evaluated using independent-samples t test or Mann-Whitney U test, and baseline and follow-up variables were evaluated with paired t tests for normally distributed variables or Wilcoxon signed rank tests for variables with a skewed distribution.
Agreement in baseline estimation was evaluated using the kappa statistic, the proportions of agreement and the intra-class correlation coefficient.
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CEO of Professional Science Editing for Scientists @ prosciediting.com