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The aim of this study was to determine the clinical and microbiological features, outcome, and baseline variables predictive of death, in HIV-associated TBM.
The aim of this prospective, observational cohort study was to determine the clinical and microbiological features, outcome, and baseline variables predictive of death, in Vietnamese adults with HIV-associated tuberculous meningitis (TBM).
Three baseline variables predictive of best response to add-on omalizumab were ascertained.
When adjusting for the aforementioned risk factors, baseline variables predictive of PAD outcomes were high pulse pressure, renal dysfunction (higher ACR), and poor glycemic control (higher HbA1c).
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For the subgroup based on a baseline variable predictive of poor survival, it was estimated that 220 patients would be needed for 80% power to detect a hazard ratio (HR) of 0.66 (masitinib plus gemcitabine versus placebo plus gemcitabine) using a two-sided log-rank test with a significance level of 0.05.
Other variables predictive of ICS change were short-acting β-agonist use, socioeconomic status, and rate of asthma consultation at baseline.
Other variables predictive of unsuccessful treatment were a greater use of short-acting β-agonist and more asthma consultations at baseline.
To identify variables predictive of appropriateness and explore management alternatives.
Logistic regression was applied to identify variables predictive of BCS.
Here we use data from a recent Internet based smoking cessation trial in order to investigate which of a set of a priori chosen baseline variables are predictive of missingness, and the evidence for and against the "missing=smoking" assumption.
Three baseline variables were predictive of death by multivariate analysis: increased TBM grade [adjusted hazard ratio (AHR) 1.73, 95% CI 1.08 2.76, p = 0.02], lower serum sodium (AHR 0.93, 95% CI 0.89 to 0.98, p = 0.002) and decreased CSF lymphocyte percentage (AHR 0.98, 95% CI 0.97 to 0.99, p = 0.003).
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CEO of Professional Science Editing for Scientists @ prosciediting.com