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Baseline values were assessed in comparison with a reference population [ 21].
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The baseline value was assessed 1 day before the injury.
Food intake was restricted the night before the test, and the baseline value was assessed 1 day before TBI.
A total of 1,942 patients who did not have baseline NLR values were assessed in the post hoc analysis of the first measured NLR values and outcomes.
Statistical significance between baseline and follow-up values were assessed using the paired t-test for continuous measures and McNemar's test for categorical measures.
Potential correlations amongst baseline parameters and between baseline parameter values and reproducibility values were assessed using Spearman's rho coefficient test (two-sided).
Bootstrap values were assessed with 1000 replicates.
Within-group comparisons between the baseline and end of treatment value were assessed using a Student's paired t test.
Overall changes (across both groups) in measures were examined using paired t-tests where there was no evidence of differences in change between groups and regression models using follow-up values while controlling for baseline values were used to assess any association with compliance.
Data from those individuals with at least 5 episodes of RME were also informally examined to assess if baseline values were increasing with each subsequent episode of RME.
Baseline values were excluded from this analysis.
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