Adjusted total UPDRS score mean change from baseline were 4.20 units for the rasagiline 1 mg group and 3.56 units for the rasagiline 2 mg group.
More precisely, changes in responses of low-firing units are proportional to absolute firing rate changes (since f0 ≪ g0), while response differences for the high-baseline units become proportional to the relative changes from the baseline activities (since f0 ≫ g0).
Participants were asked to wear the unit for one baseline week prior to initiation of the intervention, and for the 6-week duration of the program.
Such a finding would provide a basis for support of fold baseline as the appropriate unit for ALT expression in clinical trials.
(c) For a regulated NSR pollutant, when a project involves multiple emissions units, only one consecutive 24-month period must be used to determine the baseline actual emissions for the emissions units being changed.
(d) For a regulated NSR pollutant, when a project involves multiple emissions units, only one consecutive 24-month period must be used to determine the baseline actual emissions for the emissions units being changed.
After correcting for potential bias due to regression to the mean, baseline AIRg and DI were no longer significantly associated with rate of change in DI (regression coefficients were reduced to −0.0056 ± 0.0123 log DI unit per year/log AIRg unit, P = 0.65, for baseline AIRg; −0.0009 ± 0.0096 log DI unit per year/log DI unit for baseline DI, P = 0.92, respectively).
Baseline AIRg and DI were significantly negatively associated with rate of change in DI (regression coefficient ± SE = −0.031 ± 0.0107 log DI unit per year/log AIRg unit, P = 0.004, for baseline AIRg; −0.0337 ± 0.0103 log DI unit per year/log DI unit for baseline DI, P = 0.0014, respectively).
The following formula was used to calculate the percentage change from baseline for the two clones: (1−(B2M −/− sample %/B2M −/− baseline %)/(B2M+/+ sample %/B2M+/+ baseline %)) × 100.
