The significantly higher Hb change from baseline to the last available data in the DHA-PQP group is in line with this observation.
Data within the ranges 2,000 to 2,800 and 4,600 to 5,400 cm−1 were used in fitting the polynomial baseline curve to the data.
The baseline to 4-month data informs the first transitions; the 4-month to 12-month data informs all subsequent transitions, until year 10.
However, as around 50% of losses occurred prior to baseline measurement, the data needed to assess the effect of the loss to follow-up were not available.
The Wilcoxon's signed ranks test was used to examine the dependent variables and compare the baseline data to the postintervention data.
The resulting curves provide the pre-anthropogenic baseline to which the Holocene data points can be compared.
To reduce interindividual variability and day-to-day baseline variability, the data were referred to the second individual baseline value (just before stimulation).
Passing the filtered data through a second high-pass filter removed the baseline offset to make the data more amenable to photon counting based on a simple threshold.
This gives us a baseline result with which to compare the data integration results.
Transition probabilities derived from the complete eligible, BCMS natural history data were applied to the baseline data to predict outcomes over the subsequent 10 years to assess how well it matched the observed data from which the model was derived.
