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General linear mixed models were used to determine the effects of the intervention on weight, adiposity, health behaviors, and eating and exercise self-efficacy by examining changes in children and parents from baseline to completion of the study (18 months).
Physicians and patients were blinded to centralized A1C data from baseline to completion of the study.
Figure 3 shows Kaplan-Meier plots for PFS and OS stratified by change in patients' CTC status from baseline to completion of the first treatment cycle (CTCKIN).
The primary outcome was established as changes in adherence to recommended clinical practices from baseline to completion of the project and impact on health outcomes.
As in the pivotal trials of galantamine-IR, the primary endpoints were; change in cognition (measured by a modification of the ADAS-cog, the ADAS-cog11) and global rating (CIBIC-plus) from baseline to completion of the trial.
To address this directly in a clinical setting, the present large study analyzed the changes in CTC status, or CTC kinetics, occurring from baseline to completion of the first cycle of a new line of systemic therapy in patients with MBC.
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For each parent the actual time from baseline to completion for each of three later assessments was included to control variation in when parents returned forms; the cube root of time was used as it provided the best fit to account for non-linear change over time.
In this manner, a locus being replicated before ARS1412 is predicted to show an increase over the baseline (i.e., to result in values higher than 1) in advance of ARS1412 replication before returning to the baseline after completion of DNA replication at both loci.
In particular, the percentage change in PSA from baseline to the completion of initial 12-week evaluation, or date of withdrawal from study if earlier, is presented in a waterfall plot.
There was no significant change in any group on nutritional intake or physical activity from baseline to the completion of the trial.
As previously reported [ 4], GHS participants who completed the 6-months coaching program reported statistically significant improvements in weight (−3.9 kg); waist circumference (−5.0 cm); and BMI (−1.4 BMI units) from baseline to the completion of coaching [ 4].
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