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Correlation analysis between the differences in brain activation when the task was given with placebo versus MP showed a significant correlation with baseline metabolism (r = 0.48, p<0.05); the lower the metabolism at baseline the greater the attenuation of the activation by the task by MP.
This means that the more leakages occurring at the baseline, the greater the decrease.
The more troublesome the symptoms at baseline, the greater the potential benefit from surgery.
Moreover, the higher the ΔPP was at baseline, the greater the increase in CO in response to fluid infusion [ 25].
94– 98 Additionally, cohorts have examined the effects of tenofovir on patients with baseline CKD and found the worse the dysfunction at baseline, the greater the negative impact on the kidney function.
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For cognitive/psychological and behavioral factors, variables were assessed as pairs baseline levels and change scores because baseline levels and change scores are confounded with each other; the worse the baseline score, the greater the improvement in that factor.
From the Phase 3 data, it appeared that the higher the burden of inflammation, as assessed by baseline CRP, the greater the increase observed in SCr.
A significant correlation was observed between the change in the proportion of Treg cells among CD4+ T cells and the changes in CDAI score from baseline to week 52: the greater the increase in proportion of Treg cells among CD4+ T cells from baseline to week 52, the greater the improvement in CDAI score during the same period (ρ = −0.346, P = 0.031).
The higher the baseline SSS for erosion, the greater the expected difference in SSS erosion change scores between the standard and anti-TNFα groups.
Nevertheless, the baseline mean leakage correlates with mean leakage for the follow-up week (r = 0.539; P = 0.047), which means that the greater the baseline mean leakage, the greater the leakage in the follow-up.
Indeed, a prior analysis showed that the greater the baseline C-reactive protein (CRP) and the greater the change in CRP with tofacitinib treatment, the greater the change in SCr [ 7].
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