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A baseline sputum sample was obtained within 14 days of the first study period when subjects were administered a single dose of randomised treatment.
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Bacillary load in baseline sputum samples was classified according to the number of acid-fast bacilli seen per high power field (HPF).
Baseline sputum samples were assessed for 69 patients.
Baseline sputum samples were from the most recent clinic where patients were not experiencing PEx.
The median volume of the sputum sample was 2.6 ml, ranging from 1.0 to 5.0 ml.
Each sputum sample was used to generate a decontaminated preparation.
Second, only 1 sputum sample was collected from each participant.
Information on how to produce sputum and characteristics of a good sputum sample was less often provided.
In the event that sputum samples are requested, numerous delays can and do arise: The delay until the first sputum sample is taken.
Patients unable to produce a spontaneous sputum sample but with an adequate induced sputum sample were considered "sputum-scarce".
Patients also had to be available to collect the first baseline sputum sample prior to commencing treatment, and all sputa were collected over 12 hours to reduce random variation between samples.
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