Exact(3)
Further analysis revealed that baseline spine size does not influence the extent of shrinkage.
Most patients were male, had a mean age of 44 years, a mean baseline spine pain of 77 mm, and a mean BASDAI score of 55 mm.
Serial sagittal images of the thoracolumbar junction and lumbar spine (T9 L5) were obtained and coded for degenerative change using the atlas of Jarosz et al, 9 as previously described in the baseline spine MRI study.
Similar(57)
Intra- and interreader reliability was strong for baseline SPARCC spine and SI joint MRI scores.
The primary endpoint was the percentage change from the baseline lumbar spine BMD.
Therefore, 95% of analysed subjects had baseline lumbar spine DXA measurements, and 93% had baseline hip DXA measurements.
As expected, the baseline lumbar spine BMD for the OLES study was lower in the patients receiving placebo in the previous TOP study.
The baseline cervical spine imaging rates at the intervention and control sites (61.7% and 52.8%) were much lower than the 76% seen in the validation study and not as balanced as planned.
Study findings will aid us in planning properly-powered clinical trials that examine if baseline lumbar spine stiffness and flexion-relaxation 1) are associated with baseline patient-centered outcomes; 2) predict improvement in patient-centered outcomes after treatment with SM; and 3) improve along the course of treatment.
Patients were stratified according to time since menopause (less than or more than 3 years) and baseline lumbar spine BMD (normal or osteopenic) and were randomly allocated to receive iv ibandronate 0.5 mg, 1 mg or 2 mg, or placebo every 3 months as well as daily calcium supplementation.
In the group who received alendronate for a total of 10 years, BMD increased at multiple sites compared with baseline; lumbar spine BMD continued increasing throughout treatment, whereas from 5 years onward other sites showed stable or decreasing BMD (Bone et al 2004).
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