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Stratford and Riddle have shown a large increase in MCID with increasing raw baseline score for the RMQ [ 32, 33].
A statistically significant interaction meant that the intervention had different effects according to the baseline score for the outcome variables.
The mean baseline score for the EQ-5D HSI was 0.778 for the panitumumab+FOLFOX4 arm and 0.756 for the FOLFOX4 alone arm.
The mean baseline score for the EQ-5D HSI was 0.769 in the panitumumab+FOLFIRI group and 0.762 in the FOLFIRI alone arm.
In the latter, all comparisons were adjusted for socioeconomic disadvantage, 23 age at randomisation, sex, and baseline score for the outcome (where collected).
a Estimated from ANCOVA model with factors for treatment and centre and covariates for baseline throat soreness and baseline score for the relevant variable.
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The outcome is considered the CES-D baseline score for those included; the course starts shortly thereafter.
Furthermore, the median baseline score for this capability was relatively high at 54% leaving less room for large improvements to be made.
Table 2 shows the baseline scores for the outcome variables.
Internal consistency for baseline scores for the current sample was α = 0.89.
We expect the mean baseline scores for the outpatients to be somewhat lower, however not considerably.
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