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bSubject was unable to have baseline scan due to radiochemistry failure.
Six patients (three with and three without brain metastases) underwent both baseline and day 8 [11C]lapatinib-PET scans, except one who was unable to have the baseline scan due to radiochemistry failure (tumour receptor status and injected radioactivity and mass for patients scanned are summarised in Tables 2 and 3, respectively).
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One CTR and one ADT participant dropped out prior to baseline scanning due to concerns about 'feeling closed in' in the scanner.
Quick scan - This is quicker than a regular scan due to aggressive timing and only scanning select ports.
Of the four Controls studied at follow-up, three (2 male; mean age 5.5) had suitable baseline and follow-up scans; due to the small number with repeat neuroimaging, we excluded Controls from formal longitudinal analyses, and provide only a description of change for informal comparison with the group receiving intervention.
Setae are visible in the tubulin scans due to autofluorescence.
The pretherapy In scans and the posttherapy Lu scans were congruent, with a somewhat stronger signal in the Lu scans due to higher levels of activity given.
Therefore, the scanning results from a database reduced in size, yet containing data from only one species, will provide a measure of the increase in sensitivity to the baseline scan that is due simply to a reduction in search space.
First, all scans of each subject were registered to the first baseline scan to correct the position of each scan without changing brain size.
In another subject, the baseline scan was not assessable due to tissue extravasation of the radiotracer.
Missing HRQL data at baseline were due to administrative errors.
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