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Baseline renal dysfunction was defined as a creatinine level greater than 100 μmol/L during the first day of ICU admission (CLS reference range less than 100 μmol/L for adult females).
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Renal dysfunction was defined by an increase in creatinine ≥ 200% from baseline in the first five postoperative days or new renal replacement therapy at any point during hospitalisation.
Daily serum creatinine (sCr) levels also were collected during urea therapy; renal dysfunction was defined as an increase in sCr of ≥0.3 mg/dL compared with baseline levels.
Incident renal dysfunction was evident in 34%; those who developed incident renal dysfunction had higher mean baseline AER (P < 0.001) and were generally younger (P = 0.02) than those who had normal AER throughout follow-up.
Renal dysfunction was defined as an increase in serum creatinine level by more than twice the baseline level during the postoperative period in patients with previously normal renal function.
No renal dysfunction was observed during urea therapy.
No renal dysfunction was observed in 213Bi-DOTATATE-treated mice after the doses were applied.
Severe renal dysfunction was rarely reported.
Mild hepatic and renal dysfunction was suspected.
Renal dysfunction was reported in 117 (33%) patients.
Renal dysfunction was defined as Creatinine > 120 μmol/l.
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