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In the univariate analyses, nearly all of the baseline predictors were found to be significant.
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Regarding relapse, no significant predictors were found.
The only significant predictor was found to be baseline EQ-5D score.
Here again, no significant predictor was found.
With the previousstandard of care (pegylated interferon-alpha and ribavirin), baseline predictors were regularly used to determine treatment candidacy, and recently, IL28B genetic polymorphisms have been identified as the strongest baseline predictors of treatment response.
With the previous standard of care (pegylated interferon-alpha and ribavirin), baseline predictors were regularly used to determine treatment candidacy, and recently, IL28B genetic polymorphisms have been identified as the strongest baseline predictors of treatment response.
Baseline predictors were pros of smoking, pros of quitting, self-efficacy, and intensity of smoking.
Yet the role of IL28B genotype testing and other baseline predictors is less clear in the setting of DAAs.
Exploratory univariate analysis of age, disease stage, baseline PS, baseline CA19-9, and baseline white cell count were found to be not statistically significant predictors of PFS or treatment completion.
No predictors of nonunion were found.
No other predictors for seronegativity were found.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com