We sought a method for any reader to quantify the limit, imposed by variability, to sustainably observable R2 between any baseline predictor and response marker.
A baseline predictor is applied to these, and the predictor is re-trained for the next time interval while including the newly introduced instances.
Using the real data from a food wholesales company we show how the prediction accuracy can be improved using this strategy, as compared to the baseline predictor as well as an ensemble of predictors.
As well as a new dependent variable, these models also employ the change witnessed at the previous national election as a baseline predictor (i.e., the difference between the vote share obtained in the previous national election and the one before that), in order to provide a strong test of Wikipedia's usefulness.
At present, treatment cannot be individualized on the basis of any baseline predictor of response.
We also implemented a baseline predictor by random selection of five solvent grid points that are less than 5Å from the protein surface.
Pred = baseline predictor.
Notably, CXCL13 levels emerged as the only baseline predictor of US outcomes in our cohort.
Population β is the effect of the baseline predictor on the later outcome in the population.
Two study variables, Baseline predictor and Follow-up outcome, were created (see Figure 1).
For simplicity, there was not modeled any direct effect from the baseline predictor to baseline health.
