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Readers graded baseline photographs from all participants and all follow-up photographs from 402 untreated eyes.
Pretreatment baseline photographs of the right and left nasolabial folds (NLFs) were taken for each subject.
Fractal dimension was measured from baseline photographs using a computer-based program following a standardized protocol.
The number of people with baseline photographs suitable for grading was 736 (77%).
Of these, 736 (77%) had baseline photographs suitable for retinal vascular geometry grading and were included in this longitudinal study.
Retinal vascular caliber was measured from baseline photographs using a computer-based program following a standardized protocol.
When compared to baseline photographs, the skin showed a more homogenous surface and the skin texture appeared even better.
Patients were screened for eligibility according to the 5-point Merz scale 14 at visit 1 (day 0), when baseline photographs were taken.
Onset of treatment effect was defined as the day that the observer noted a decrease in glabellar muscle activity compared with baseline photographs and videos.
We therefore aimed to determine whether retinal vascular D f measured from baseline photographs of eyes without retinopathy is associated with subsequent risk of retinopathy development in a cohort of type 1 diabetic subjects.
The photographs were graded by an experienced ophthalmologist [EA], blinded to baseline exposure status, using the International Clinical Diabetic Retinopathy Disease Severity Scale [67].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com