Table 1 Expression Levels and Disease Rating of Transgenic Lines Constructs Transgenic line Expression level (µg/mg of total protein) Disease rating Dm-AMP1 Rs-AFP2 % DLA (M.
Using gene expression profiling we have demonstrated a similar whole transcriptome gene expression patterns in prostate cancer cells from human and rat prostate cancer cell lines both at baseline expression levels and after treatment with physiologic concentrations of the proposed chemopreventive agent Selenium.
We firstly screened baseline TPM3 expression levels in 10 HCC cell lines.
First, we determined baseline megalin expression levels in LLC-PK1 cells, an epithelial cell line derived from kidney proximal tubule, and in BN cells, a cell line derived from rat yolk sac.
In line, the baseline p53 expression level varied widely between the different cell lines without any specific pattern.
The forced over-expression of THBS4 in cancer cell lines significantly suppresses their colony forming abilities and growth, regardless of their baseline THBS4 expression levels.
Using 59 cell lines of the NCI-60 human tumor cell panel, the investigators measured the baseline gene expression levels of 22,238 gene probes (representative of 14,500 human genes) using the Affymetrix HG-U133A chip [ 17].
Likewise, colon tumor cells that show resistance to arsenic-induced killing also show baseline gene expression levels that are similar to each other, yet quite distinct from the leukemia tumor cell lines.
The baseline gene expression levels of 14,500 well characterized human genes were associated with the GI50 data of the NCI-60 tumor cell line panel from the developmental therapeutics program (DTP) database.
