Sentence examples for baseline level of expression from inspiring English sources
Myostatin precursor was overexpressed at approximately 10 fold the baseline level of expression detected in the Saline, LacZ, and dnMSTAT groups (Fig. 8E).
Despite apparent differences in the baseline level of expression of the three gene transcripts, all genes showed similar expression levels (signal) following transfection.
We also wanted to incorporate some of the findings relevant to the saline control group as they enabled us to have a measure of the baseline level of expression of different genes.
The hsp27 transcript level decreased at 4 days and continued to decrease at 15 days of thermal exposure relative to control; however, The expression level slowly increased towards baseline level of expression as the exposure period was extended for 30 days and 2(c)).
Because the cholesterol biosynthetic pathway is exquisitely controlled by multiple regulatory mechanisms14, we investigated the baseline levels of expression of several key proteins in the pathway.
The decrease in expression of Klf2 in response to IL-1β was not affected by either SB203580 or U0126, although LY294002 (which itself increased expression of Klf2 mRNA, Fig. 3B) restored the baseline levels of expression (Fig. 6C).
The few differences in gene expression between wild-type and Meig1-deficient mice detected by DNA microarray studies may reflect an artifact arising from low baseline levels of expression.
Until recently most conventional approaches have restricted their focus to only those genes which have satisfied multiple different criteria including size of fold change, significant p-value (often accompanied by additional requirements related to passing tests correcting for multiple comparisons), and certain minimum baseline levels of expression on at least one side of the comparison.
Interestingly, both inhibitors reduced the baseline level of Endo180 expression indicating that there is a low-level of autocrine TGF-β stimulation in U87MG cells.
