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In both groups, total B-cell counts decreased by approximately 40% from the baseline level in the RCT originating study.
At 300 minutes, MAP returned to the baseline level in the HSL group while a 51% and 30% decrease was observed respectively in the NC and HSB groups.
Adjustment for baseline level in the analysis allows a finer difference of 4.0 umol/l to be detected between arms (EPIC test-rest correlation of 0.67).
The study subjects had a 4.7% increase in lumbar spine mass in the PTHrP group, associated with an increase of 60% above the baseline level in the serum osteocalcin, a measurement of bone formation.
The median (interquartile range) baseline level in the total cohort was 6.2 (3.0–10.0) ng/l, and 27 (14%) patients had values at or above the 99th percentile (14 ng/l) at baseline.
Assuming that the minimum requirement of amino acids for biomass maintenance is the baseline level in the blood, the amino acid influx was scaled between two to seven times depending on the specific amino acid.
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Lastly, intervention compliance was found as a mediating factor between the baseline level in these factors and changes in alcohol consumption.
The effect of the drug was not specific, however, in that the lowest effective dose that attenuated ethanol-seeking behavior also suppressed responses below baseline levels in the S−/CS− control condition.
In addition, higher soil moisture levels resulted in greater reductions in white blood cell counts relative to baseline levels (−0.95, −0.43, and 0.34 × 109/L relative to baseline levels in the very muddy, muddy, and dry treatments).
Circulating plasma testosterone and androstenedione concentrations were not markedly affected by any gonadal treatment, except that they remained at baseline levels in the bilaterally castrated rams, comparable to the ewes.
Mean SUVmax, PSA and ALP changes at 6 and 12 weeks as a percentage of baseline levels in the five subjects (A to E).
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