Sentence examples for baseline in the severity from inspiring English sources

Patients who had at least a 1-grade improvement from baseline in the severity of their headaches based on patient diaries were considered to be severity responders.

The primary outcome of interest is the change, from baseline, in the severity of symptoms after 2 weeks of treatment.

The primary outcomes of interest are the 2-week change, from baseline, in the severity of CSDD scores and the Quality of Life AD (QoL-AD) scores.

The mean change from baseline in the severity of glabellar lines at maximum frown according to the Merz 5-point scale at later time points (3 months, 4 months, and 5 months postinjection) was still significant (P < 0.001) at −1.95, −1.53, and −0.95, respectively, compared with baseline.

Treatment response in this study was defined as ≥50% reduction from baseline in the severity scores of DRS-K in the same manner as a previous study comparing the effectiveness and safety of atypical antipsychotic medications in the treatment of delirium [ 26].

Secondary end points included change from baseline in the BPI severity index and functional index, overall survival, duration of pain relief, relative change in bone ALP and PSA, and assessment of AEs.

Relapse was defined as meeting one of the following three criteria: (1) a 1-point increase over continuation baseline in the CGI-severity score; (2) reported adverse event of treatment-emergent hypomania, mania, or depression; or (3) discontinuation due to treatment-emergent clinical worsening or insufficient clinical response.

Weekly means of change from baseline in the average pain severity ratings from patient diaries were analyzed using a likelihood-based, mixed-effects model repeated measures (MMRM) approach that used all available observations.

The model-based mean change from baseline in the BPI pain severity index at week 17 was −0.63 (95 % CI −1.44 to 0.19; P = 0.24), and the BPI functional interference index mean change from baseline at week 17 was −1.01 (95 % CI −1.83 to −0.20; P = 0.0310).

The primary endpoint of percentage change from baseline in the Target Plaque Severity Score at week 4 demonstrated statistically significant improvement for ointment 1 [least squares mean (LSM) –54·4%] vs. vehicle 1 (LSM –41·5%), but not ointment 2 (LSM –24·2%) vs. vehicle 2 (LSM –17·2%).

In Study II [ 16], patients in the duloxetine group who had <30% reduction from baseline in pain severity on the BPI 24-h average pain severity scale, had their dose increased directly to 120 mg/day and continued on that dose for the remainder of the study.