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During isoniazid therapy, a significant increase from baseline in the proportion of IFN-γ responders to the 10-kDa culture filtrate protein, Rv2031, Rv0849, Rv1986, Rv2659c, Rv2693c and the recombinant Rv1737 protein was observed (p⩽0.05).
4 The treatment with OXN-PR did not worsen bowel dysfunction in our patients, even in those subjects with manifest constipation at baseline, with a nonsignificant decrease from baseline in the proportion of patients complaining of constipation after 28 days of treatment and without an increase in laxative consumption.
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Exploratory endpoints include change from baseline in FPG, the proportion of patients achieving HbA1c <7%, effects on various biomarkers of beta-cell function including insulin, C-peptide, HOMA-B and proinsulin/insulin ratio, and the annualized slope of glycemic control (coefficient of durability).
The baseline difference in the proportion of patients receiving biological DMARD was a result of chance (not systematic).
Improvements in BCVA from baseline and in the proportion of patients gaining at least 10 and at least 15 letters with dexamethasone IVT 0.7 mg peaked at 2 months and declined thereafter.
To determine if the effects in the Faah−/− mice were related to a correction in the baseline alterations in the proportion of NPCs within the SGZ converting into neurons or astroglia in the GFAP/Gp120//Faah−/− mice, we performed analysis on brain sections double labeled for BrdU and GFAP.
The CGP contributed to a 15 percentage point reduction (from a baseline of 39 percent) in the proportion of both boys and girls ages 0-5 who suffered from an illness (generally flu or cold) in the 30 days prior to the survey.
Direct observation comparisons from the Chi-square statistical test identified no significant differences in the area-level PA between schools during lunchtime breaks at baseline for the proportion of children in sedentary behaviour, moderate intensity PA (MPA) and vigorous intensity PA (VPA).
Of the patients with assessments at Day 14, 38.1% (16/42) had ≥2 g/dL reduction in hemoglobin concentration from baseline, though the proportion with a decrease of ≥4 g/dL had fallen to 7.1% (3/42) (Table 7).
Characteristics at baseline and the proportion of responders in each group were compared by using nonparametric tests.
Secondary efficacy measures at week 12 (LOCF) included changes from baseline in FPG and total daily dose of insulin (TDDI), the proportion of patients achieving a decrease in A1C ≥0.5% from baseline, and the proportion of patients achieving A1C <7%.
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