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As of May 2010, 95% of baseline enrolment within APPLES has been completed.
These patients were invited for a follow-up visit 7 9 years after baseline enrolment.
Table 1 describes the characteristics at baseline (enrolment) according to the pregnancy status in the course of follow-up.
Baseline enrolment covariates included US geographical region (east, midwest, south, or west) and insurance type (Medicare Advantage or Private Healthcare Maintenance Organization).
Participants Patients who at baseline (enrolment) were treatment naïve to β blockers (n=5640), diuretics (n=6346), statins (n=6146), and calcium channel blockers (n=6294).
Median pre-enrolment serum creatinine concentration was 86 μmol/L (74 102) vs. baseline (enrolment) creatinine 74 μmol/L (56 86), P = 0.3 (Wilcoxon-paired test).
Similar(48)
Cognitive testing was performed on children at baseline after enrolment in the intervention study after which all three groups were randomised to three trial arms of the study.
Participants will receive 150 Kenyan Shillings (KES) at the baseline visit (enrolment) and 150 KES for each subsequent study visit (6 and 12 months) to reimburse them for their time.
Both intervention and comparison participants will be asked to complete surveys at baseline (upon enrolment in the study when their infant is less than 6 months of age), and when infants are aged 6 and 9 months.
All patients should have recorded headache diaries for 4 weeks (baseline phase) before enrolment to assess disease activity (disease duration, headache degree, and attack frequency).
At enrolment baseline blood samples were collected from each individual.
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