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After 10 min. of supine rest, baseline data were acquired during a further 10 min. of rest, where the subjects refrained from speaking and from unnecessary movements.
Baseline data were acquired from 11 healthy adult, male subjects.
At the first pre-therapy imaging session, baseline data were acquired with both baths for each patient.
30 Before transient hypoxia-ischaemia, baseline data were acquired after stabilisation of the animal in the MRS system.
The timeline of the protocol was defined as follows: baseline data were acquired after 30-min stabilization from surgical procedures and the time point was defined as time-point "A" according to the timeline of group T. 1 hr, 2 hrs, 3 hrs and 4 hrs after time-point A was defined as time-point B, C, D and E respectively.
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Baseline and follow-up FDG data were acquired according to our 'low-dose protocol', as two 6 min frames over the liver and reconstructed with 3i21s and a 5 mm Gaussian filter.
In all the subjects, behavioral and structural MRI data were acquired at baseline (on the day of the beginning of the motor training) (time 0), at the end of motor training (after two weeks ±1 day) (time 1), and 3 months later (±1 day) (time 2).
ADNI PET image data were acquired at baseline.
While this higher pressure was maintained, blood flow data were acquired for baseline and the breath-holding/hyperventilation tasks.
Resting state fMRI data were acquired at baseline and post stimulation and were analysed using an independent component analysis approach.
MSQ data were acquired at baseline, 4, 8, and 16 weeks by using the Last Observation Carried Forward (LOCF) method.
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