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To compare continuous baseline data between the cohorts, non-parametric Kruskal-Wallis ANOVA was performed, followed by Mann-Whitney U-test.
Baseline data between the four groups did not differ significantly.
It resulted in incomparable baseline data between the two groups.
Baseline data between the two groups were compared using t-tests or Chi Square tests.
There were no significant differences in the baseline data between the groups.
There was no difference in clinical baseline data between the sitagliptin and control arms.
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There were no statistically significant differences in any of the demographic and baseline data between those who completed the study and those who lost to follow-up at 6 month.
To compare the demographic and CSF baseline data between groups, the Mann–Whitney U test was used for continuous variables, and the Pearson χ test was used for dichotomous variables.
Although propensity-score matching was used to balance the baseline data between treatment groups, the differences between the groups were quite significant (Table S1) and the potential residual confounding might therefore still be present, particularly unobserved selection bias.
The study subjects were required to have at least 6 months of quality-controlled baseline data (between index date and the later of patient registration date, practice Vision date [date the practice started using the computer software Vision] and Acceptable Mortality Reporting [AMR] date).
This finding might explain the significant increase in the positive detection rate of toxigenic C. difficile and the incidence of toxigenic C. difficile per 1,000 admissions observed in 2009 as compared to the baseline data between 2004 and 2008.
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