The objective of this secondary data analysis was to compare baseline demographics and clinical characteristics and treatment outcomes of CJS-involved participants to participants with no apparent CJS involvement entering a national multisite web-based psychosocial addiction treatment study (WEB-TX) (Bickel et al., 2008; Campbell et al., 2012).
The first level of data analysis was undertaken of baseline and endline data collected in October 2010 and December 2012, respectively, to describe the intervention and outcome variables for each of the study sites.
The flow chart of screening, baseline measurement, enrollment, randomization, intervention, and data analysis is shown in Fig. 1.
47 individuals were excluded at registration because of previous malignancy, incomplete staging or lack of other baseline data, thus this analysis was confined to the remaining 377 patients.
Permission for the Centre for Global Health, Trinity College Dublin to use the de-identified baseline data for secondary analysis was obtained from both World Vision Ireland and World Vision Uganda and ethical approval was obtained from the Health Policy and Management/Centre for Global Health Research Ethics committee, Trinity College Dublin.
In cross-sectional analysis using baseline data, multiple linear regression analysis was used to examine mean difference in HbA1c across CRP categories.
In cross-sectional analysis using baseline data, multiple linear regression analysis was used to examine the mean differences in FEV1 and FVC across CRP categories.
We, therefore, have disregarded the analysis of the baseline data, which was only used as an inclusion criterion for the prospective trial.
However, the effect of this was that cases with missing baseline data were excluded from the analysis and the analysis may no longer be considered ITT.
In this paper, a cross-sectional analysis of baseline data was conducted.
