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Significance of activation was tested by comparing activation with baseline activity in the same ROIs.
The tetracycline (Tc -dependent sysTc -dependentn" versystemrtTA system) dinplays a baselits activity in the uninduced state, severely limiting its ponential applicability in human gene therapy.
She found that people who started with below-average baseline activity in the right anterior insula responded well to cognitive behavioral therapy, but not to the antidepressant.
Thus, Professor Mayberg found that she could predict a depressed person's response to specific treatments from the baseline activity in the right anterior insula.
The original tetracycline-dependent system using the rtTA (Dox-on) transactivator displayed a baseline activity in the off state but improved versions are now available and need to be evaluated in a single-rAAV-vector strategy.
Rest influences baseline activity in the brain.
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Moreover, simultaneous transient increases in 100 500 Hz activity were present in several other channels that did not meet criteria for detection, either because signal amplitude was not high enough relative to the baseline activity in that channel to exceed detection threshold, or because there were too few signal peaks outside of the threshold values.
A truly frightening experience appears to heighten baseline activity in circuits involving the amygdala, a subcortical area that registers threat, and makes it harder for higher areas of the brain to inhibit amygdala response.
In fact, baseline activity in cells responsive to the cued location was somewhat elevated.
The observed suppression of calcium activity may reflect a decrease in baseline activity in GABAergic cerebellar neurons during the stimulus presentation (Fig. 4f).
These results strongly suggest that speed-accuracy instructions modulate baseline activity in pre-SMA, thereby modifying the amount of evidence that must be accrued prior to reaching a decision threshold.
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