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M. acuminata Calcutta 4 and Cavendish Grande Naine whole plants (Musa International Transit Centre accessions ITC0249 and ITC0654) were selected for transcriptome analysis based upon their known contrasting resistance to M. musicola.

A multivariable risk-stratified approach does not conduct multivariable analysis directly on the clinical trial data, but rather, risk-stratifies the study population based upon their known risk factors using a multivariable risk prediction tool, which should be developed and validated using previous observational and experimental studies[ 22].

To establish whether the two cell lines exhibit the expected differential pattern of cell-cycle arrest in response to ionising radiation (based upon their known p53 status), cultures were exposed to 4 Gy of γ-irradiation (preliminary observations indicated that this dose was suitable for inducing cell-cycle arrest without inducing a substantial cell kill).

This study was biased toward collecting subjects with pulmonary disease as the probands of each family were all collected based upon their known diagnosis of pulmonary fibrosis.

All the molecules listed within each network are connected based upon their known relationships or functions within the GeneGo Pathways Knowledge Base.

A panel of 15 proteins was selected for investigation based upon their known responsiveness to changes in axonal and synaptic vulnerability (see Introduction; Table  1) (29– 31).

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Both approaches map functional polymorphisms based upon their linkage with known polymorphic markers and benefit from knowledge of the population structure for an effective experimental design.

The four base pair core, CCAT, is scored at 100% for each base plus 2. Flanking bases vary in score from 0 to 1 based upon their frequency in known YY1 binding motifs.

The aim of this approach is to identify the genes and proteins involved in PCD based upon their evolutionary relatedness to known apoptosis machinery molecules.

Nonetheless, our recent P K-edge XANES study of a model system allows us to infer the speciation of adsorbed TPP based upon the known adsorption and precipitation mechanisms on a goethite surface in the presence of Ca2+ [7].

To determine a possible role for TDP-43 in Alzheimer's disease (AD), a site-directed caspase-cleavage antibody to TDP-43 based upon a known caspase-3 cleavage consensus site within TDP- 43 at position D219 was designed.

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