Sentence examples for based upon the structure from inspiring English sources
This scoring matrix is derived by a similar procedure as the BLOSUM matrices (Henikoff and Henikoff, 1992 , 1993 are done, based upon the structure alignments of structurally similar protein pairs.
As the first step to design even more effective drugs based upon the structure of fisetin, the present study investigated the structural requirements for the anti-amyloidogenic activity of fisetin by comparing the effects of several structurally related flavonoids on Aβ fibril formation in vitro.
Two new agents based upon the structure of the clinically active prodrug laromustine were synthesized.
A novel series of cyanoguanidine-piperazine P2X7 antagonists was designed based upon the structure of A-740003.
"Based upon the structure of this group, their associations and connected events, there is a reasonable suspicion that these persons pose a threat to national security," the document said.
Her new "Arena," which is based upon the structure of ballroom dances, will be presented by Susan Marshall and Company Thursday through Saturday nights at the Bessie Schonberg Theater.
A series of m-carborane derivatives was prepared based upon the structures of antiestrogenic drugs and their activities were evaluated by estrogen receptor alpha (ERα) binding assay and transactivation assay using human breast cancer cell line, MCF-7 cells.
We then validated the system using six additional pesticides of which tow were predicted to be P-gp inhibitors and four were predicted to be noninteractors, based upon the structure-activity analyses.
Sections of the sequence that show strong similarity may be used to construct a 3D model based upon the structures of the templates.
Based upon the structures of the anti-hapten antibodies described above, we identified a position for introduction of a cysteine mutation, which shall enable hapten-positioned covalent coupling of thiol-containing hapten payloads.
Modeling the missing residues in the human pol γ-α structure based upon the secondary structure prediction algorithm built into the I-TASSER server resulted in two short alpha helices connected by a short loop, which orient this element toward the DNA binding cleft of the enzyme (fig. 4 B).
