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The seed regions and contrasts used for these analyses were all based upon the corresponding univariate whole-brain comparisons described above.
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The triple ISC built based upon the thresholds corresponding to the three major immunoglobulin isotypes (IgG, IgM and IgA) showed the highest impact on survival mean time, which was reduced 6.6 days in average in those patients showing a ISC IgGAM = 0 (Fig. 1; Additional file 1).
The identification of this gene as CES2.1 is based upon the identity of the corresponding predicted protein with the deduced amino acid sequence for opossum CES2.1.
In addition, Collins et al. developed a method for calculating an interaction score for protein pairs based upon the presence and absence of the corresponding proteins in affinity purification mass spectrometry experiments [15].
Primers for RT-PCR were designed with Software OLIGO 4.0 based upon the sequences of the genes corresponding to the identified spots on the chip.
Computations were based upon the sample-specific mAE (mAE↔E) and the corresponding mTOP deviations (ΔmTOP↔ΔCt) for each sample tested vs the control sample: NHBE.
Therapeutic choices for metastatic tumors are, in most cases, based upon the histological and molecular analysis of the corresponding primary tumor.
The results presented in Table 6 demonstrated 19 of 19 reference strains of type A avian influenza viruses detected and correctly identified by corresponding A/HN subtype, based upon the specific HA and NA gene sequences revealed in the assays of each specimen.
Accordingly, we have previously developed the cap-analysis gene expression (CAGE) method ([10] [11]), which is based upon the production of short (20 21 nt) tags corresponding to the 5' end of capped RNA transcripts.
GO categorized each promoter with respect to protein function, showed the number of promoters within each category, and reported a corresponding p-value based upon the calculations.
For RT-QPCR studies, the DNA content of an unknown sample is then estimated by translating the value of the measurand associated with a sample into its corresponding DNA concentration based upon the equation relating to the calibration curve.
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