Sentence examples for based upon sequence similarity from inspiring English sources

One way to address this biological question is to ask which proteins in ProMed4 have no ortholog that is, no gene of similar apparent function (based upon sequence similarity)—in Pro9313.

PfEMP1 proteins have multiple receptor-like domains that group into different homology types based upon sequence similarity.

Based upon sequence similarity over the length of kinase domains (File S1), 993 Ser/Thr kinases from 303 prokaryotic genomes have been clustered into 270 clusters (File S2) with minimum sequence identity of 40% within a cluster.

Initial assignments of orthology of these mammalian genes were based upon sequence similarity, but were subsequently confirmed by performing genomic neighborhood and phylogenetic analyses (see below).

We clustered the 562,321 protein-coding sequences that occur among 191 completely sequenced prokaryotic genomes from 15 higher level taxa with standard procedures (Enright et al. 2002) into groups based upon sequence similarity threshold.

These isoforms have been categorised into classes based upon sequence similarity: six in the α subunit class, three β, three γ, and one each of δ, ε, θ and π.

Annotation of putative function from unknown sequences is largely based upon sequence homology (similarity) to proteins of known characterised function and particularly the presence of specific sequence/structure motifs (such as the Rossmann fold or the P-loop motif).

Therefore, it remains challenging to predict regulatory activity based solely upon sequence similarity, or vice versa.

Consensus sequences derived from Clusters were entered into the software that utilizes custom BLASTx, RPS-BLAST, and relational mySQL databases to identify potential functional assignments based upon sequence and functional domain similarity matching.

In a further analysis, we explored gene families based upon protein sequence similarity which grouped sequences into no more than four using a similar methodology to Klenk et al. and Heidelberg et al. [ 57, 58].

Based upon the sequence similarity within the multi-gene family of patatins, a highly conserved target sequence (635 nts) of patatin gene pat3-k1 [GenBank accession no. DQ114421] in potato plants (Solanum tuberosum L). was amplified for the construction of a patatin-specific hairpin RNAi (hpRNAi) vector.