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Bacterial GH 18 chitinases are classified into three subfamilies A, B, and C (again, based upon sequence homology).
Based upon sequence homology and genome location at least seven small RNAs are predicted riboswitches.
ProValt parsimoniously clusters nonredundant peptides falling within user-defined criteria to protein homology groups based upon sequence homology.
Hand annotation of many probesets based upon sequence homology allowed us to input a very large and complete data set into the MetaCore pathway analysis.
Based upon sequence homology within the ATPase core, these can be assigned into some 24 distinct subfamilies (Flaus et al., 2006).
Annotation of putative function from unknown sequences is largely based upon sequence homology (similarity) to proteins of known characterised function and particularly the presence of specific sequence/structure motifs (such as the Rossmann fold or the P-loop motif).
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Based upon sequence homologies, NCX1n corresponds to NCX1a, whereas NCXh is NCX1b.
The PD-proteome contained known plasmodesmal proteins and some inferred plasmodesmal proteins, based upon sequence or functional homology with examples identified in different plant systems.
PfEMP1 proteins have multiple receptor-like domains that group into different homology types based upon sequence similarity.
Non-homologous end joining (NHEJ), which does not depend upon sequence homology, is the key repair pathway during the G0/G1 stages of the cell cycle [10].
The bioinformatic identification of orthologs frequently depends upon sequence homology since "similar sequence" usually implies "similar function".
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