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In this paper, the GmGER genes were also divided into three subgroups based upon sequence conservation.
GLPs could be further divided into three subgroups based upon sequence conservation [ 37].
Based upon sequence conservation and function, we refer to CNE-3 as chicken FIRE.
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Clu has two predicted domains based upon primary sequence conservation with the human protein (KIAA0664); an undefined 'Clu' domain (residues 424 666) and a C-terminal tetratricopeptide repeat (TPR) domain, which may serve as a scaffold to mediate protein-protein interactions (Cox and Spradling, 2009).
The estimation is based upon sequences of independent and identically distributed random variables.
The predictions, based solely on local structural similarity, are more accurate than those produced by ConSurf (Glaser et al., 2003, 2005), a protein surface mapping tool which depends upon sequence conservation and which to our knowledge, is the only available tool that maps sequence conservation to protein structure.
Based on sequence conservation, most zebrafish orthologues of human PTP genes were readily assigned.
Often gene functions of chicken genes were annotated based on sequence conservation without further functional evidence.
Based on sequence conservation across species [14], this SNP is predicted to be relatively undamaging to protein function.
We identified 64 sRNAs in Shigella, which were experimentally validated in other bacteria based on sequence conservation.
The first method (Simple Conservation or SC) is based on sequence conservation.
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