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Our findings contribute to phenotype characterization of BCG substrains and provide new elements to consider for the design of diagnostic tools, drug targets and a new vaccine against tuberculosis based upon protein expression through quantitative statistical analysis.
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The acceptor scaffolds were based upon proteins with the Protein Data Base designation 1d3bb, 1lgya, 1ku2a and 1iwla respectively.
Prediction of the radiation sensitivity based upon the expression of Rad51 protein is apparently not straightforward (Vispé et al, 1998; Yanagisawa et al, 1998; Yanez and Porter, 1999; Kim et al, 2001).
In mammals B cell development is divided into stages (pro-, pre-, immature and mature B cells) based upon the expression of various cell surface proteins [14]; it is during the pre-B cell stage that Ig heavy chains are first displayed on the cell surface.
In most cases, however, a single diagnostic marker is not available, and more complex decision rules will be required to define a sensitive population based upon, for instance, mRNA expression, protein expression or DNA copy number.
Patient probability of response ranging from 0 to 100% was observed based upon the expression or phosphorylation of a small set of ligands, receptors and signalling proteins.
Three Halomonas TD strains were then constructed based upon these expression systems that enabled interchangeable and controllable gene expression.
Based upon neuronal expression, amphetamine is thought to affect norepinephrine analogously to dopamine.
Unsupervised hierarchical analysis clustered CLL samples based upon miRNA expression (Figure S2).
Thereafter, were sorted based upon the expression of CD25 and CD127.
Other investigators have used immunomagnetic separation based upon cytokeratin expression (Hu et al, 2003).
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