Sentence examples for based upon previously identified from inspiring English sources

New anthrax lethal factor inhibitors (LFIs) were designed based upon previously identified potent inhibitors 1a and 2. Combining the new core structures with modifications to the C2-side chain yielded analogs with improved efficacy in the rat lethal toxin model.

The analyses allowed identification of experimentally denoted genes within defined functional pathways and networks based upon previously identified gene gene or protein protein relationships.

The individual proteins chosen for examination in our molecular experiments were based upon proteins previously identified in mice carrying a spontaneous genetic mutation that confers protection on axons and synapses (but not neuronal soma) in both the central and peripheral nervous systems: the Wallerian degeneration slow (Wld s ) mutant mouse (19– 22).

Autophagic vacuoles were identified based upon previously established criteria.

For the methylation analysis, the primers for the three Igf2/H19 DMRs were designed and based upon previously published sequences.

The integration of lactic acid fermentation and Reverse Electro-Enhanced Dialysis (REED) is investigated based upon previously developed mathematical models.

The protocol was based upon previously published IHC [ 40].

Enterocyte isolation was perfomed based upon previously published methods [ 20].

Solid and enzyme loading concentrations were based upon previously optimized experiments for dilute acid pretreatment [ 17].

The conceptual design of tools is based upon previously published work [ 10, 11].

Chemical structures of the antagonists are depicted in Additional file 2. Doses were based upon previously published reports [ 14, 19].