Sentence examples for based upon previously determined from inspiring English sources

Based upon previously determined antagonists for chemokines, we devised a set of screens that mimicked the behaviour of a low-level pharmacophore: it specified that molecules should have molecular weight >500, contain at least two 5- or 6- membered aromatic rings, and at least one nitrogen atom.

We performed multivariable logistic regression to determine predictors of willingness to participate, with predictor variables chosen a priori based upon previously published data or suspected influence on willingness to participate in research.

For the methylation analysis, the primers for the three Igf2/H19 DMRs were designed and based upon previously published sequences.

The integration of lactic acid fermentation and Reverse Electro-Enhanced Dialysis (REED) is investigated based upon previously developed mathematical models.

The protocol was based upon previously published IHC [ 40].

Autophagic vacuoles were identified based upon previously established criteria.

Enterocyte isolation was perfomed based upon previously published methods [ 20].

Solid and enzyme loading concentrations were based upon previously optimized experiments for dilute acid pretreatment [ 17].

The conceptual design of tools is based upon previously published work [ 10, 11].

Chemical structures of the antagonists are depicted in Additional file 2. Doses were based upon previously published reports [ 14, 19].

In this EMSA, instead of interrogating the binding capacity of the two alternative nucleotides of a SNP as is routinely done in an EMSA experiment, we applied it to completely methylated and completely unmethylated promoter regions, that were chosen based upon the location of previously determined transcription elements (53).