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Even without identifying the β-arrestin-related MG/BG target, it may be possible to develop compounds with better pharmacological properties based upon our finding differences between the potencies and efficacies of BG and MG for β-arrestin2 activation.
Based upon our finding of a new pharmacophoric group in inhibition of PTP1B and the structural characteristics of the binding pocket of PTP1B, a series of bis-arylethenesulfonic acid ester derivatives were designed and synthesized.
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Recommendations for planning the survey design are presented based upon our findings.
Based upon our findings, recommendations are made as to the potential use of the AE-based technique in asphalt binder specification.
Based upon our findings that an increase in SFA levels compromises DNA damage response while inhibition of FAs synthesis enhances these cellular events, lowering the cellular level of FAs might reduce the risks of cancer development.
Based upon our findings at the TNF-α promoter [11], it was our prediction that high level IL-10 synthesis stimulated by LPS and immune complex (IC) would be suppressed by the parasite, even though low level LPS-induced IL-10 was not affected.
Some currently unexplained findings of meta-analyses appear in a new light based upon our findings.
Based upon our findings we question the role of GM-CSF and neutrophils during AIDS-associated TB.
Given these circumstances, the Canadian legislation took a complicated regime and, based upon our findings, made it even more complex.
Based upon our findings, we are able to elaborate on how to further enable demand-based provision of long-term care by means of modularity.
Based upon our findings, this investigative tool may assist in discriminating between persons with and without BMLs, but this discriminatory ability is weak at best.
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CEO of Professional Science Editing for Scientists @ prosciediting.com