A method for development of actuator structures based upon model insight is presented.
A new modified metal-organic framework MOF-5 MM) has been designed based upon the insight from the organic and inorganic fragments.
One crucial consideration is based upon the insight that a relation is the 'ground' of its terms as well as 'founded' upon them.
In the late 1990s, a similar approach to computer ethics, called "value-sensitive computer design", emerged based upon the insight that potential computer-ethics problems can be avoided, while new technology is under development, by anticipating possible harm to human values and designing new technology from the very beginning in ways that prevent such harm.
Based upon molecular insights from the X-ray structures of inhibitor-bound HIV-1 protease complexes, we have designed a series of isophthalamide-derived inhibitors incorporating substituted pyrrolidines, piperidines and thiazolidines as P2-P3 ligands for specific interactions in the S2-S3 extended site.
Based upon our previous insight into a contact-dependent effect of hMSC on APC phenotype and function [12], along with the linking of this effect to STAT3 activation [13], we now tested whether a similar contact-dependent STAT3 activation is also induced in tumor cell-APC interaction.
Figure 1 exemplifies the model that was developed based upon mentioned theoretical insights.
A first principles two-parameter model, based upon the newly obtained insights, is proposed.
In this regard, he has offered advice and insights based upon CDF's experience running a similar community program in the Fruitvale area of Oakland, California.
To be sure, the geometric framework for Weyl's construction of the objective four-dimensional world of relativity is based upon the Evidenz available in "essential insight", which is limited to the simple linear relations and mappings in what is basically the tangent vector space to a point in a manifold.
