Sentence examples for based upon gene expression from inspiring English sources
Despite a genomic revolution in biological sciences, clinical medicine has yet to integrate diagnostics based upon gene expression into practice.
Based on the phenotype, macrophages are classified into classically activated/(M1) and alternatively activated/(M2) which are further sub-categorized into M2a, M2b, M2c and M2d based upon gene expression profiles.
As an approach to achieving this goal, mechanistic interpretations based upon gene expression changes that are determinants of adverse toxicological outcomes were applied to the analysis of low-dose gene expression profiles.
These data indicate CMCs and PBMCs do have unique gene expression patterns and represent distinct functional phenotypes based upon gene expression.
Age-grading methods that delineate chronological age, using accurate molecular surrogates based upon gene expression profiles, will allow quantification of the longevity-reducing effects of vector control tools aimed at the adult, female mosquito.
The resistance index, however, was based upon gene expression levels prior to drug treatment, and a drug-induced activation of the DNA repair response would therefore not be detected.
To classify a particular single cell as a developing RGC based upon its gene expression profile, genes strongly associated with the RGC marker neurofilament light (NF68) were determined.
We tested this hypothesis with an experiment, based upon global gene expression, to identify networks of genes in which expression patterns in inguinal fat of mice have been altered by the nutritional environment during early post-natal development.
If we accept this assumption, then 81 of our 82 tumor samples were correctly classified based upon their gene expression signature.
This will allow for the physician and patient to have a more informed discussion as to how to proceed with clinical treatment options based upon the gene expression profile.
Based upon our gene expression and mass spectrometry results, we suggest the Aacp114k paralogue identified in the current study is a prominent protein component of barnacle cement in A. amphitrite.
