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To identify genes with non-sinusoidal oscillatory patterns, signed WGCNA (Langfelder and Horvath, 2008) was used to detect modules based upon gene coexpression.
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Interestingly, cells meeting classical definition of fibrocytes based upon the coexpression of CD34, CD45, and Col-Iα1 in the absence of CD14, were rare in both sets of animals and not significantly altered between groups.
A recent study by Tipton et al. [ 33] used data mining to identify 64 genes that are core components of the kinetochore complex, and then sought evidence of other members of the complex based upon coexpression analysis and/or protein-protein interactions in public domain data.
Recently, researchers used reannotation microarray expression data to identify lncRNAs and predicted functions of lncRNAs based on coding-noncoding gene coexpression network [ 23].
Moreover, these studies are all based upon the Tsc1 gene.
Fourteen 8q genes were within the top 68 genes based upon univariate analysis (Table 3).
Because of the complex regulation, coexpression analysis based upon microarrays does not link MITF to its known target genes in different cell types.
Gene coexpression, based on k-means analysis, cluster identifier.
Based upon the current genome annotation (2,838 annotated genes in total), each TSS covers 1.52 genes.
Recently, Ma et al. [ 54] presented an Arabidopsis gene coexpression network based on partial correlation analysis.
A weighted gene co-expression network analysis[ 77] was used to construct gene coexpression networks based on a Pearson correlation coefficient >0.75.
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