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Notably, in a recent study, gene expression patterns were shown to be predictive of major cytogenetic patterns seen in meningiomas (chromosome 22 or 22q loss, loss of 1p36 alone, complex karyotypes with loss of 1p36 and/or 14q and diploid) based upon altered expression of a combination of genes within the regions of altered dosage and genes outside these regions [ 42].

Similar(59)

Here again, however, statistical approaches have proven effective, and prior work has identified "cytokine activity signatures" embedded within the psoriasis transcriptome, based upon comparison of genes altered in psoriasis lesions with those altered in KCs stimulated by specific cytokines in vitro[ 5, 6, 16, 18].

Thus, the system needs to be altered, based upon new principles that consider in their core human rights and the rights of the child in particular.

Several lines of evidence support an adaptive model of fetal nutrient transport by which transporter function is altered based upon nutrient availability and fetal demand.

In biochemical studies on fish, the gill activities of PMCA and NCX, which are altered based upon physiological needs and environmental changes, have been proposed as being associated with transepithelial Ca2+ transport [ 9, 23].

To address the CMAS attack some approaches have been advanced based upon sealing the TBC or altering the TBC composition.

Nevertheless, the IVAN study's recommendation to alter dosing based upon ATEs or death rates clearly implies that there must be a belief that there is a systemic effect of these intravitreal agents.

Just as every conductor's expert interpretation of a musical score will be slightly different based upon his or her judgment, we alter our model's forecast based on our interpretation of current conditions.

Microcystis may also incorporate different amino acids during light and dark periods based upon amino acid availability that may alter the variant of microcystin synthesized [ 87].

Therefore, this study does not provide a rationale for altering vaccination programmes based upon a subsequent risk of type 1 diabetes.

Each of the candidate genes examined for association with pediatric bipolar disorder were selected largely because they are involved with neurotransmitter systems hypothesized to be altered in mood disorders based upon pharmacological response or animal models.

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