Sentence examples for based upon a conserved from inspiring English sources

We have found that the structure of plant Rho GTPases is based upon a conserved G-domain architecture, but structural differences were found concerning the insert region and switch II region of the protein.

Our current model for FHE2 function is based upon a conserved increase in SQN mRNA levels in Ler-0 and Fe-1 compared to Col-0.

Structural homology among Helitrons is often used for prediction and characterization, and is based upon a conserved 3′-stem-loop (hairpin) formed upstream of the 3′-CTRR terminus.

The proteins of this family are unified by their sharing of a common structural organization that is based upon a conserved ATPase domain of ~225 residues referred to as an AAA protomer.

In summary, a consensus is emerging that the design of the larger phage genomes, such as the T4- and SPO1-likes (Stewart et al. 2009; and probably large viruses in general), is based upon a conserved core genome of essential genes and a large and variable set of facultative genes.

However, since the query used to look for ancient introns is based upon selecting conserved sequences, the introns found in ancient protein modules could also represent a sample of a larger number of randomly distributed introns and not be specific for ancient genes.

Phylogenetic tree reconstruction based upon 727 conserved coding genes demonstrated that H. parasuis, A. pleuropneumoniae, and H. ducreyi were grouped into a subclade (Figure 2).

It can be justified to adjust alignments based upon expected conserved biochemical or structural features (with the explicit assumption that these are conserved consistent with the evolutionary homology and therefore can be used as alignment 'anchors'anchors

Based upon conserved synteny between human and mouse, Holland inferred the existence of an ancestral NK-like cluster that encompassed these same four genes, in addition to other related homeodomain genes [ 19].

The author has previously noted [67] that improved search algorithms based upon conserved function and "information content" are needed to assess similarity of proteins in cases in which strong evolutionary selection is suspected.

Our approach is based upon conserved domain composition, taking into account both previously identified domain signatures in Pfam [ 12] and TIGRFAM [ 13] and any remaining potential novel domains identified in the Arabidopsis proteome using independent methods (see Methods).