We developed a web-based tool for identifying an individual's risk of developing colorectal cancer based on the person's family history.
We also present a web-based tool for identifying and evaluating CRISPR target sites and demonstrate that gRNAs designed with this tool are highly specific.
To do so, we used SNAP (http://www.broadinstitute.org/mpg/snap/; 83), a web-based tool for identifying proxy SNPs, to generate a list of all SNPs in LD (at an r ≥ 0.5) with any of our eQTLs (r was based on HapMap LD, although results using 1000 genomes-based LD were broadly equivalent; data not shown).
Using DAVID 2008, a web based tool for functional annotation clustering [ 9], we identified among regulated transcripts functional clusters of genes coding for proteins involved in 1) intracellular protein transport, 2) clathrin coated vesicle transport, 3) lysosome and lytic vacuole, 4) regulation of JNK activity and 5) endocytosis (Table 3).
Portfolio builder is a tool for identifying securities based on customized selection criteria.
In conclusion, we developed a new, refined, diagnostic tool for identifying LVNC, based on an a priori assessment of the trabecular architecture in healthy volunteers.
The specificity of the XRF tool for identifying PBDE based on bromine content in products is expected to decrease over time due to PBDEs no longer being the dominant brominated flame retardant and due to the subsequent use of a wider variety of alternative brominated flame retardants.
This method based on MOMP is a useful screening tool for identifying BH3 mimetics with selective toxicity against breast cancer cell mitochondria protected by the three major Bcl-2 anti-apoptotic proteins.
