Sentence examples for based tests of association from inspiring English sources

In Table 3, the p-values obtained by using our REG test (for details see Statistical analysis: regression based tests of association section) are consistently lower than those obtained by using the LOCAL test.

In a conditional analysis performed by using weighted regression (for details see Statistical analysis: regression based tests of association section), when we conditioned on the most significant SNP, rs28936, no residual association was provided by the remaining four SNPs, suggesting no evidence of multiple effects operating across the studied SNPs.

This was computed with TRANSMIT but other family based tests of association have also been which could still have confounded linkage with association.

The possible role of the functional -1612 5A/6A polymorphism of the MMP-3 gene in the susceptibility to ischaemic heart disease (IHD) was investigated in a well-defined Irish population using two recently described family based tests of association.

One explanation for lack of replication by the case control studies is that the family based tests of association have not been able to distinguish very well between evidence of linkage and evidence of association.

The possible confounding of linkage with association in family samples already showing linkage at 6p22.3 might be revealed by testing genes closely linked to DTNBP1 for allelic association and by restricting family based tests of association to only one case per family.

Results from global gene-based tests of association are included in Table 1.

Table 2 lists results for global gene-based tests of association with case/control status using the minimum p-value permutation (Min-P) test.

Multi-generational pedigrees may provide more information on inheritance patterns observed on genotype data, which improves the quality of family-based tests of association.

Single-point genotype- and allele-based tests of association were performed using a chi-squared test or fisher exact test.

Mapping resolution in the CC is typically of the order of 1 2 Mb, due to the increased extent of observable recombination in the population and the use of haplotype-based tests of association [ 18, 22– 25].