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Moreover, interestingly, GATES, a p-value based test, is more powerful than PLINK and FBAT, which use raw genotypes, in these simulation scenarios.
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Home- based testing was more effective than clinic-based testing.
Molecular based tests are more specific as in our study none of patients with other diseases tested positive.
Subgroup analyses within studies based on small numbers seemed to indicate that immunochemical based tests were more sensitive in detecting early stages of cancer than guaiac based tests.
To detail, the haplotype-based pedigree tests had enhanced statistical power when the disease of interest was mainly contributed by rare haplotypes (with multiple rare alleles), and the rare variants based tests were more powerful when disease was independently caused by rare variants.
In contrast, MS-MLPA allows interrogation of individual CpG site methylation across the entire promoter region and, as a PCR-based test, is more readily adapted to the clinical setting.
Our results identify limitations in evaluating disease status by CgA and identify that a PCR-based test is more sensitive.
Agarose gel based tests were also performed.
However, based on our experiences, Fisher test is more robust and can be used in situations when a small portion of the p-values are very small; while the Z test is more powerful when the effect sizes are similar (e.g., the p-values don't differ much) for all of the age groups.
The political test is more easily stated.
Panel based unit root test are more preferred to individual time series ones given the better power properties of the former test.
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