The diversity of potential regulatory sequences, difficulty predicting biologic regulation based solely on a consensus miRNA binding site, and the increasingly apparent need for confirmation in living cells indicate that additional, cell-based studies should be used in the future to address transcriptome regulation by miRNA.
Further clinic-based studies should be carried out, with the aim to define possible therapeutic guidelines for these patients.
This study similarly conveyed that product-based studies should be preferred for PAS 2050, to minimise the uncertainties associated with technology models in process-based studies.
Population-based studies should be conducted to evaluate male and female fertility, conception delay, growth retardation, and specific birth defects.
Therefore, the support from these voxel-based studies should be regarded as important evidence for a structural brain change in this region but requiring replication in future samples.
More proteomic-based studies should be performed to clarify the functions of autophagy-related proteins in cancer and cancer-associated stromal cells.
Therefore, Neale et al. [ 31] advocated that any positive association findings in gene-based studies should be confirmed in a different population using a larger sample size.
Thus, we cannot completely exclude the possibility that a true genetic effect was overestimated, and the results of hospital-based studies should be explained with caution.
