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Many familial and population based studies have demonstrated the role of genetic factors in susceptibility to multiple sclerosis (MS).
Several microarray based studies have demonstrated 21 to 34 differentially expressed miRNAs between ccRCC and normal kidney tissue [ 11].
Population based studies have demonstrated that men and those of Polynesian ancestry have higher mean SU concentrations [ 25, 26], and high baseline levels may mean that therapeutic SU targets are more difficult to achieve.
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Previous population-based studies have demonstrated worsening breathlessness as functional status deteriorates, 33 even in the absence of demonstrable cardiorespiratory disease.
Epidemiological and clinic-based studies have demonstrated a close association between migraine and sleep disturbance.
Numerous cell culture, animal, and human-based studies have demonstrated the potential health benefits of consuming whole-grain rice and some of its phytochemical fractions.
European population-based studies have demonstrated that depression and/or anxiety occur two to three times more often among migraineurs than in the general population [55, 56].
Both clinic and population-based studies have demonstrated that, compared to EM, CM is associated with greater migraine-related disability [7, 8], reduced quality of life [9], increased resource utilization [8], and increased medical and psychiatric comorbidities including depression [10].
Poplation-based studies have demonstrated that compared to EM, CM is associated with greater migraine-disability, reduced quality of life, increased medical and psychiatric comorbidities, increased risk of medication overuse [16, 23, 50].
This hypothesis is supported by the fact that some laboratory-based studies have demonstrated that a reduced ROM at the hip joint level leads to overloading of the symphysis [72].
Recent population-based studies have demonstrated that the use of intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC) is associated with a decrease in the rate of common bile duct (CBD) injury.
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