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Laboratory based studies comparing the efficacy of recombinant human collagen types I and III as corneal substitutes for implantation, showed that the chemical and mechanical properties of the hydrogels was similar; however, the implants manufactured from synthetically cross-linked recombinant human collagen type III (RHC-III) were found to possess superior optical clarity [21].
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The hospital based studies compared the use of oral amoxicillin for management of WHO defined severe pneumonia to either injectable penicillin or ampicillin for 48 h.
This is followed by a numerical based study comparing the heuristics with all possible spanning tree based spines for sample topologies.
We also recommend a national large community based study comparing the urban with the rural population.
We found slightly greater effect sizes in community based studies compared with hospital based and intensive care unit based studies.
We restricted our review to cohort studies with more than 1,000 participants, as we thought it was more likely for there to be more missing data in follow-up measurements of exposures in large cohort studies (typically population based studies) compared to small cohorts (often based on a specific clinical population).
There is only one UK study which details bed occupancy which is the major non drug expense and this is the Manchester based study comparing best supportive care to gemcitabine.
However, there are few observational register-based studies comparing the effectiveness of different biologic drug classes in real life circumstances.
Such an algorithm will enable large-scale, population-based studies comparing the effectiveness of different DMARD regimens.
To date, large, population-based studies comparing the frequencies of genes encoding the Rib, alpha and beta C proteins among invasive and colonizing isolates have been limited.
Such an algorithm will enable large-scale, population-based studies comparing the effectiveness of different DMARD [disease-modifying antirheumatic drug] regimens.
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