Sentence examples for based solely on sequence from inspiring English sources

Given this consistent bias, it might be difficult for any method based solely on sequence analysis to recover some (for example, rarely mutated) cancer genes.

Given that the topological relationships of these DBMs are completely different, at this stage, it would be difficult to detect the hidden similarities among these DBMs based solely on sequence information, without 3D structural information.

While we could identify candidate binding elements in this region based on biological inference [9], the level of resolution provided by mouse/human sequence comparison did not permit us to predict putative binding elements based solely on sequence conservation.

Based on our experience, we believe that the comparison of miRNAs and mRNAs expression profiles therefore provides a useful complement to pure computational predictions based solely on sequence information.

To avoid this force field dependence due to significant differences in point charges between AMBER variants, and obtain SASA quantities that were based solely on sequence and structure, reported SASA values were calculated using the VEGA package [28], with a probe sphere radius of 1.4 Å and a point density of 24 points/Å24

64 Amongst them, methods based solely on sequence information have been reported.

Although no clear sequence motif emerged, we were able to use machine learning approaches to accurately discriminate between ORC-associated sequences and ORC-free sequences based solely on primary sequence.

The 3D structure of proteins depends on their amino acid sequence [1] but cannot be predicted based solely on that sequence, except for relatively small proteins [2].

The mismatches between HD and sequence data suggests that the best calls based solely on individual sequence information, does not necessarily represent the actual variants, which might cause a negative bias in the assessment of imputation accuracy.

At this point, we re-evaluated the initial sequence pattern for PHI-BLAST because it was based solely on the sequence compilation of the Zic family genes.

The goal of placing the human genome sequence in the public domain is shared by the Wellcome Trust, which has also said it will challenge any patent claims based solely on DNA sequence.