Sentence examples for based solely on functional from inspiring English sources
Much of the previous work has focused on estimation techniques that use very simple cost models based solely on functional units (FUs).
We derive the cyclic voltammogram for H on Pt(111) and Pt(100), based solely on density functional theory calculations and standard molecular tables.
Network analysis can enhance the utility of even simple transcriptomic studies, as we illustrate in Fig 3. Expression data-mining based solely on gene functional annotations is limited by incomplete annotations and the fact that key regulators of disease progression may not be differentially expressed.
The finding that the inflammatory state of perturbed cells could be predicted based solely on this global functional annotation of lipids indicates that the protein state of a cell mediating the inflammatory phenotype is strongly dependent on and intertwined with the cellular lipid state.
"The real challenge was to analyze the vast amount of data for which no reference genome was available and to identify and produce full-size functional enzymes based solely on information obtained from billions and billions of short snippets of DNA sequences," he said.
Metabolic pathways may have common origins with overlapping substrate specificity, and so caution should be used in interpreting functional data based solely on DNA sequence analysis.
The functional adaptations within the GH18 family highlight the challenges of assigning protein functions based solely on sequence similarities.
While similar active sites provide a measure of functional similarity, inferring homology based solely on the observation of a similar helix-turn-helix motif is questionable.
Recently, methods and algorithms were developed for de novo discovery of mutated driver pathways and functional modules in tumors based solely on cancer genomic data [ 18- 20].
We have developed a sensitive, simple, and fast method for automatically detecting functional modules in tumors based solely on patterns of recurrent genomic aberration.
A fourth strategy for expanding the functional profiles (AS-sem) is based solely on GO.
