Variations in other opioid receptor genes were not associated with alcohol dependence in the same large, family-based sample in which the association with OPRK1 was reported (17).
These figures draw upon a population-based sample in which the majority of persons report only low-level pain and patients with severe pain are rare [ 31].
Of note, for comparison purposes, we also estimated a model for the Australia-based sample in which all participants who declared themselves to be of Asian ethnicity were excluded (remaining n = 157).
However, the patterns identified in this population-based sample, in which the prevalence of CAM was relatively low and few subjects used more than one modality [ 15] may not be applicable to breast cancer survivors.
In contrast to studies of clinical samples, reports based on population-based samples in which self-report or direct assessments of psychiatric disorders are collected from both parents and offspring are rare.
This can also be considered a strength of the study, showing the power of the method to assign ancestry even in a clinically based sample series, which perhaps would not be expected to display the population structure seen in grandparental sampling schemes.
This study addresses issues of functional status in persons with chronic fatigue syndrome and other fatiguing illnesses in a population based sample, which can be generalized to all persons with chronic fatigue.
We confirmed the results of another recent study that used this study design in a population based sample from one hospital in Israel, which reported on a composite of hypertension disorders and other complications.
These results are in line with a previous cross-sectional study evaluating the epidemiologic determinants of vaginal pH in the same-population based sample from Guanacaste (enrollment data only) in which vaginal pH was strongly related to age and menopausal status [ 23].
The internet based sample was split in half which allowed for the factor structure to be explored in half the sample, and then confirmed it in the second half of the sample.
This exercise reveals that our estimations are based on a sample in which firms with more than 50 employees are somewhat overrepresented.
