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Three randomised trials have investigated the clinical efficacy of using platinum based regimens for the treatment of TNBC, [54], [55], [56] with further randomised trials evaluating the addition of platinum derivatives to standard adjuvant therapy (NCT01150513 & NCT01216111).
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The aim of this study was to assess the offset of the pharmacodynamic effects and the safety profile of a remifentanil based regimen for the provision of analgesia and sedation in mechanically ventilated ICU patients with varying degrees of renal impairment.
So, we selected cisplatin plus etoposide based regimen for this patient on the 29th postoperative day.
Results of Sofosbuvir based regimens for hepatitis C (HCV) recurrence after liver transplantation are available from well-designed clinical trials.
Patients whose disease control worsened were offered follow-up and protocol based regimens for intensification of treatment.
To continue the increasing trend of utilizing perioperative chemotherapy, clinical studies should address the overarching issues of predicting which patients will more likely benefit from chemotherapy, identifying particular chemotherapy regimens for specific patient subsets, and developing more efficacious non-cisplatin based regimens for patients who are cisplatin-ineligible.
From January 2010 we reverted back to triple ARV based regimen for all women as the national guideline was revised in line with WHO recommendation.
The trial was terminated early on the advice of the data safety monitoring committee because of a significant treatment difference in favour of patients randomised to the amlodipine based regimen for two secondary end points (stroke and total cardiovascular events).
All participants were required to have achieved viral suppression on a LPV/r based regimen for at least 3 months prior to randomization.
Median number of emetic episodes with cisplatin based regimens in the 1970s and the 1980s for germ cell tumors on day 1 was ten and decreasing on subsequent days [ 2].
Folic acid based regimens should not be used for the prevention of cardiovascular events in people with kidney disease.
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